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Acknowledgment

The authors thank Dr. Hitoshi Kato and Dr. Tetsuya Mitarai for performing renal biopsies and for helpful discussions concerning pathological findings.

Conflict of interest

K.A. has received research grants from the pharmaceutical companies Tanabe-Mitsubishi, Astellas, Pfizer, Bristol-Myers Squibb, and Chugai. The other authors have no conflicts of interest to declare. This research was not supported by any specific grant from any funding agency in the public, commercial, or nonprofit sectors.