317
Views
11
CrossRef citations to date
0
Altmetric
Research Article

Central auditory dysfunction associated with exposure to a mixture of solvents

, &
Pages 857-865 | Received 04 Jan 2011, Accepted 10 Jul 2011, Published online: 22 Sep 2011
 

Abstract

Objective: The aim of the present research was to investigate central auditory functioning in normal-hearing, solvent-exposed subjects compared to normal-hearing subjects without solvent exposure, with a comprehensive test battery of behavioural central auditory functioning procedures. Study sample: Forty-six normal-hearing, solvent-exposed subjects and 46 normal-hearing, control subjects were selected to participate in the study. Design: All subjects must present with normal hearing thresholds and absence of history of variables related to the onset of auditory dysfunction. Subjects were evaluated with a test battery comprising pure-tone audiometry (PTA), dichotic digits (DD), pitch pattern sequence (PPS), filtered speech (FS), random gap detection (RGD), masking level difference (MLD), and hearing-in-noise (HINT) tests. Results: Analyses of covariance (ANCOVA) were performed to compare the mean values of the dependent variables (results for DD, PPS, FS, RGD, MLD, and HINT) between solvent-exposed and control subjects. Age and average hearing thresholds (500–8000 Hz) were included in the analyses as covariates. Significant differences for DD, PPS, FS, and RGD results were found between groups. Conclusion: This study provides further evidence of the central auditory dysfunction associated with solvent exposure.

Sumario

Objetivo: El objetivo de este trabajo fue investigar el funcionamiento auditivo central en personas con audición normal expuestas a solventes, comparados con sujetos normales sin exposición a solventes, por medio de una batería integral de procesos de funcionamiento comportamental auditivo central. Muestra de estudio: Se seleccionaron cuarenta y seis sujetos normo-oyentes expuestos a solventes y 46 sujetos normales como grupo control, para participar en este estudio. Diseño: Todos los sujetos deb an presentar umbrales auditivos normales y ausencia de datos de variables relacionadas con el inicio de disfunción auditiva. Los sujetos fueron evaluados con una batería de pruebas que comprendió la audiometr a por tonos puros (PTA), Digitos dicóticos (DD), Secuencia de patrones de frecuencia (PPS), Lenguaje filtrado (FS), Detección de intervalos al azar (RGD), diferencia de niveles de enmascaramiento (MLD) y Audición en ruido (HINT). Resultados: se realizó el análisis de covarianza (ANCOVA) para comparar los valores de las variables dependientes (resultados de DD, PPS, FS, RGD, MLD y HINT) entre los sujetos expuestos a solventes y los del grupo control. La edad y los umbrales auditivos promedio (500–8000 Hz) se incluyeron en el análisis como covariables. Se encontraron diferencias significativas con los resultados para DD, PPS, FS y RGD entre ambos grupos. Conclusión: Este estudio proporciona evidencias adicionales de disfunción audtiva central asociada a la exposición a solventes.

Acknowledgements

The authors thank all those who participated in the study for their time, interest, and cooperation.

Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.