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Original Article

Effects of ELF Magnetic Fields on Hematological Parameters: An Experimental Model

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Pages 75-89 | Published online: 07 Jul 2009
 

Abstract

An experimental model has been developed in which mice were chronically exposed to an ELF magnetic field, under controlled conditions, with the purpose of learning its effects on peripheral blood. The OF1 mice were continuously subjected for two generations to an external magnetic field of 15 μT (rms) and 50 Hz sinusoidal waves generated by a system of Helmholtz coils designed by our Institute (BIASC). The first generation of animals was exposed for a period of 17 weeks and the second generation, born in the field, was exposed for 14 weeks. The most usual hematological parameters of mothers (12 control and 12 exposed) and daughters (30 control and 30 exposed) were analyzed. A leukopenia in exposed daughters and significant variations of platelet levels between both experimental groups were noted. Besides a slight decrease in hematocrit, red blood cell levels and hemoglobin concentration have been observed in exposed mice. The greatest changes were found in animals of the second generation.

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