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Original Article

Effects of VDT Pulsed Magnetic Fields on Gap Junctional Intercellular Communication

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Pages 313-316 | Published online: 07 Jul 2009
 

Abstract

Chinese hamster lung (CHL) cells were irradiated for 24 h with 15.6-KHz pulsed magnetic field (PMF) at 200μT peak to peak and/or 12-O-tetrade-canoylphorbol-13-acetate (TPA; 5 ng/ml). Lucifer dye was inserted into the CHL cells by iontophoretic injection. The numbers of dye-coupled cells around the injected cell were counted to determine the function of gap junctional intercellular communication (GJIC). The results showed that TPA significantly suppressed GJIC compared with the control group (p < 0.01), but video display terminal pulsed magnetic fields alone or with TPA did not diminish or enhance suppression by TPA.

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