Lipid-Laden Macrophages in Tracheal Aspirates of Newborn Infants Receiving Intravenous Lipid Infusions: A Cytologic Study

Aida L. Recalde Departments of Pathology and Pediatrics (Neonatal-Respiratory Disease Division), Children's Hospital of Los Angeles and University of Southern California School of Medicine, Los Angeles, California

Bruce G. Nickerson Departments of Pathology and Pediatrics (Neonatal-Respiratory Disease Division), Children's Hospital of Los Angeles and University of Southern California School of Medicine, Los Angeles, California

Maria Vegas Departments of Pathology and Pediatrics (Neonatal-Respiratory Disease Division), Children's Hospital of Los Angeles and University of Southern California School of Medicine, Los Angeles, California

Charles B. Scott Departments of Pathology and Pediatrics (Neonatal-Respiratory Disease Division), Children's Hospital of Los Angeles and University of Southern California School of Medicine, Los Angeles, California

Benjamin H. Landing Departments of Pathology and Pediatrics (Neonatal-Respiratory Disease Division), Children's Hospital of Los Angeles and University of Southern California School of Medicine, Los Angeles, California

David Warburton Departments of Pathology and Pediatrics (Neonatal-Respiratory Disease Division), Children's Hospital of Los Angeles and University of Southern California School of Medicine, Los Angeles, California

Abstract

Seventy-four neonates with respiratory distress syndrome had cytologic study of tracheal aspirates. Thirteen, all of whom were receiving intravenous lipid and nothing orally had abundant macrophages with foamy cytoplasm, positive for intracytoplasmic lipid by Sudan black stain, in the tracheal aspiration specimens. Cytologic surveillance of tracheal aspiration specimens may be a useful method of monitoring infants receiving intravenous lipid infusions.

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Lipid-Laden Macrophages in Tracheal Aspirates of Newborn Infants Receiving Intravenous Lipid Infusions: A Cytologic Study

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Lipid-Laden Macrophages in Tracheal Aspirates of Newborn Infants Receiving Intravenous Lipid Infusions: A Cytologic Study

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