Arnold-Chiari Malformation: Report of a Case with Contamination of Ventricular and Subarachnoid Spaces by Amniotic Sac Contents

Dimitris P. Agamanolis Departments of Pathology and Pediatrics, Northeastern Ohio Universities College of Medicine (NEOUCOM); and Children's Hospital Medical Center of Akron, Akron, Ohio, 44308

Marvin S. Platt Departments of Pathology and Pediatrics, Northeastern Ohio Universities College of Medicine (NEOUCOM); and Children's Hospital Medical Center of Akron, Akron, Ohio, 44308

John H. Vollman Departments of Pathology and Pediatrics, Northeastern Ohio Universities College of Medicine (NEOUCOM); and Children's Hospital Medical Center of Akron, Akron, Ohio, 44308

Abstract

An infant with the Arnold-Chiari malformation had a lumbosacral amniotic-central nervous system fistula that allowed massive amounts of squamous cells and lanugo hair to enter the ventricular and subarachnoid spaces causing blockage, gliosis, and fibrosis. This rare complication can be diagnosed by cytologic examination of cerebrospinal fluid and should be considered in the prognosis of Arnold-Chiari malformation and selection of cases for treatment.

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Arnold-Chiari Malformation: Report of a Case with Contamination of Ventricular and Subarachnoid Spaces by Amniotic Sac Contents

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Arnold-Chiari Malformation: Report of a Case with Contamination of Ventricular and Subarachnoid Spaces by Amniotic Sac Contents

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