Perinatal Mortality Associated with Intrauterine Infection Due to Pseudomonads

Susan Beckwitt Turkel Department of Pathology, Pediatrics, Medicine, and Obstetrics-Gvnecology, University of Southern California School of Medicine, Los Angeles County-USC Medical Center, Los Angeles, California, 90033

Cynthia W. Pettross Department of Pathology, Pediatrics, Medicine, and Obstetrics-Gvnecology, University of Southern California School of Medicine, Los Angeles County-USC Medical Center, Los Angeles, California, 90033

Maria D. Appleman Department of Pathology, Pediatrics, Medicine, and Obstetrics-Gvnecology, University of Southern California School of Medicine, Los Angeles County-USC Medical Center, Los Angeles, California, 90033

Carol A. Salminen Department of Pathology, Pediatrics, Medicine, and Obstetrics-Gvnecology, University of Southern California School of Medicine, Los Angeles County-USC Medical Center, Los Angeles, California, 90033

M. Lynn Yonekura Department of Pathology, Pediatrics, Medicine, and Obstetrics-Gvnecology, University of Southern California School of Medicine, Los Angeles County-USC Medical Center, Los Angeles, California, 90033

Abstract

Pseudomonads are common causes of nosocomial infections but are rarely implicated in perinatal disease. In a retrospective autopsy study we found that 9% of all acute congenital bacterial infections were due to Pseudomonas species. Premature rupture of membranes occurred in half the cases and clinical maternal amnionitis in two-thirds. One case was apparently nosocomial in origin. No known risk factors were implicated in any other case. Seven infants were stillborn and two died within a few hours. Congenital pneumonia, funisitis, and chorioamnionitis were found at autopsy. Intrauterine infection due to the pseudomonads poses a serious problem that has not been previously recognized.

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Perinatal Mortality Associated with Intrauterine Infection Due to Pseudomonads

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Perinatal Mortality Associated with Intrauterine Infection Due to Pseudomonads

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