![Sample our Medicine, Dentistry, Nursing & Allied Health journals, sign in here to start your FREE access for 14 days]({"type":"image" , "src" : "/sda/5944/TOC-Subject-Sample-2021-Medicine-Dentistry-Nursing-Allied-Health.jpg"})
Abstract
The present investigation was prompted by our observation of what appeared to be a circadian rhythm in the excretion of phenobarbital in rabbits 111. The effect was seen when the amount of phenobarbital excreted during each 6-hr period of urine collection was expressed as percent phenobarbital C14 per total C14 radioactivity in each sample, Since these initial observations were limited to 3 rabbits, the present investigation was undertaken to further establish the occurrence of the phenomenon. Further more, a mechanism is described through which the circadian rhythm in excretion is controlled in the rabbit.