Acute Thrombocytopenia Following Oral Cholecystography with lopanoic Acid

Abstract

Oral cholecystography is considered by the patient and the physician to be the most tolerable way of verifying gallbladder disease; nevertheless, several and serious reactions to contrast media, including renal, cardiac, and hepatic damage, have been described [1-4]

Haematological reactions are very rare. A severe thrombocytopenia following cholecystography with sodium ipodate has been reported [5]. Two cases of severe thrombocytopenia following ingestion of iopanoic acid, a widely used contrast medium, have been published [6, 7]. We wish to report a further case; to our knowledge, the first observed outside the United States