Occupational Intoxication and Long-Term Persistence of Phencyclidine (PCP) in Law Enforcement Personnel

Ferris N. Pitts Department of Psychiatry, University of Southern California School of Medicine, Los Angeles, California, 90033

Robert E. Allen Department of Psychiatry, University of Southern California School of Medicine, Los Angeles, California, 90033

Orm Aniline Department of Psychiatry, University of Southern California School of Medicine, Los Angeles, California, 90033

Lane S. Yago Department of Psychiatry, University of Southern California School of Medicine, Los Angeles, California, 90033

Abstract

By utilizing a glass capillary gas chromatographic nitrogen detector (GC²-N) method specific for phencyclidine (PCP) and sensitive to pg/mL in blood or urine samples, we have demonstrated occupational intoxication of law enforcement personnel charged with handling confiscated illegal PCP preparations. Further, we have demonstrated persistence of PCP in blood and urine for at least 6 months after the last known occupational exposure in one officer. Some aspects of the PCP problem are outlined, and possible mechanisms of the occupational intoxication are discussed.

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Occupational Intoxication and Long-Term Persistence of Phencyclidine (PCP) in Law Enforcement Personnel

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Occupational Intoxication and Long-Term Persistence of Phencyclidine (PCP) in Law Enforcement Personnel

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