Parenteral Administration of Hydrocarbons

Abstract

Two cases of subcutaneously administered hydrocarbon based products are presented and the literature reviewed. The toxicity associated with subcutaneous administration is limited to the site of injection producing cellulitis and sterile abscess formation. Management is discussed with emphasis on the importance of incision and drainage of developing abscesses. Perceived toxicity and ready availability of these products suggests that similar exposures can be expected.

Small volumes of hydrocarbons produce both local and systemic toxicity, depending upon the route of administration. Intravenous injection may produce a chemical pneumonitis similar to when these substances are aspirated. Subcutaneous injection of household insecticides or other hydrocarbon based products has produced marked cellulitis and sterile abscess formation. These effects, which may be delayed and progressive require incision and drainage. Close medical observation and follow-up are necessary when a history of injection of even small amounts of a hydrocarbon based substance is given. The injection of household insecticides or other household products for suicidal purpose is not an isolated phenomenon. The perception of toxicity and ready availability of these agents to persons with suicidal intent, suggests that similar exposures can be expected.