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Research Article

Intestinal absorption of aluminium from antacids: A comparison between hydrotalcite and algeldrate

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Pages 545-553 | Published online: 25 Sep 2008
 

Abstract

The intestinal absorption of aluminium (Al) from the antacid hydrotalcite (UltacitR) was compared with that from algeldrate (Algeldratum des-acidans) in 8 healthy human subjects in a crossover study.

The level of Al in serum (AlS) was increased in 7 out of 8 subjects 7 hr after intake of 6 g algeldrate while AlS did not rise after intake of 8 g hydrotalcite - a dose with at least comparable acid-neutralizing capacity - in any of the subjects.

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