Full Recovery After A Chloroquine Suicide Attempt

Philippe Bauer Department of Intensive Care Unit and Poison, Drug Information CenterUniversity Hospital, Hopital Central, Nancy, France

Bruno Maire Department of Intensive Care Unit and Poison, Drug Information CenterUniversity Hospital, Hopital Central, Nancy, France

Marc Weber Department of Intensive Care Unit and Poison, Drug Information CenterUniversity Hospital, Hopital Central, Nancy, France

Pierre-Edouard Bollaert Department of Intensive Care Unit and Poison, Drug Information CenterUniversity Hospital, Hopital Central, Nancy, France

Alain Larcan Department of Intensive Care Unit and Poison, Drug Information CenterUniversity Hospital, Hopital Central, Nancy, France

Henri Lambert Department of Intensive Care Unit and Poison, Drug Information CenterUniversity Hospital, Hopital Central, Nancy, France

Abstract

The nonfatal case of a 20 year-old woman who ingested 6 grams of chloroquine in a suicide attempt is reported. After initial ventricular fibrillation, she rapidly developed a pulmonary edema with cardiogenic shock. She was successfully treated with diazepam, epinephrine, dobutamine and mechanical ventilation. Plasma chloroquine levels showed an initial peak of 36 μg/mL. The patient was discharged fully recovered after 19 days. The interaction between chloroquine and diazepam is discussed, as is the need for careful management of epinephrine therapy.

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Full Recovery After A Chloroquine Suicide Attempt

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Full Recovery After A Chloroquine Suicide Attempt

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