Abstract
Background: Exfoliative dermatitis due to calcium channel blockers is a known but infrequent response. Case Report: A 77-year-old woman began treatment with diltiazem for angina pectoris. Three days later, severe exfoliative dermatitis developed. Conclusion: The present case and the others previously reported emphasize the need for greater awareness of the occurrence of adverse cutaneous reactions including toxic epidermal necrolysis, Stevens-Johnson syndrome and cutaneous vasculitis due to calcium channel blockers including diltiazem