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Original Article

Peripheral Polyneuropathy Due to Chronic Use of Topical Ammoniated Mercury

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Pages 233-237 | Published online: 29 Jul 2009
 

Abstract

Background: Despite their potentially disastrous side effects, topical mercury salts can still be found as ingredients in some over-the-counter preparations or local remedies. Case Report: Peripheral polyneuropathy as a result of chronic ammoniated mercury poisoning was studied and followed over 2 years. A 36-year-old man developed peripheral polyneuropathy following chronic perianal use of an ammoniated mercury ointment. Highly elevated blood and urine mercury levels were found. Sural nerve biopsy showed mixed axonal degeneration-demyelination. There was progressive improvement of his symptoms over 2 years but neurophysiology examination revealed incomplete recovery. Conclusion: The availability of safer drugs should result in a complete ban of these dangerous compounds.

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