Digital image analysis of bone allograft union in sheep

Franck Bresler Clinique de Traumatologie, d'Orthopédie, Rue Hermits, 49, FR-54000, Nancy, France, +33 3838575-25, -51

Patrick Simon Service de chirurgie orthopedique Pr Babin, Hopital Hautepierre, CHU, Avenue Moliere, 67098, CEDEX, FR-Strasbourg, France

Daniel Schmitt Clinique de Traumatologie, d'Orthopédie, Rue Hermits, 49, FR-54000, Nancy, France, +33 3838575-25, -51

Michel Verhelpen Orthopaedic Research Laboratory, Faculte de Medecine, Universite Catholique de Louvain, 53, avenue Mounier, BE-1200, Bruxelles, Belgique

Michèle De Gasperi Service d'Informatique Medicale, Faculte de Medecine, University de Nancy I, 9 avenue de la Foret de Haye, 54500, Vandoeuvre les Nancy, France

Christian Delloye Orthopaedic Research Laboratory, Faculte de Medecine, Universite Catholique de Louvain, 53, avenue Mounier, BE-1200, Bruxelles, Belgique

Abstract

We compared the reliability of computer-assisted radiographic analysis (CARA) and visual evaluation of radiographs to assess host-graft junctions. 68 host bone/allograft junctions were obtained from an ongoing study on bone allografting in sheep. At 6 months, the grafted tibias were explanted and healing of the host-graft junctions were macroscopically determined. 49 junctions were macroscopically healed, whereas 19 had not united. 51 (0.8) of the junctions were correctly classified by radiographs, while 63 (0.9) of the junctions were correctly classified by CARA (p = 0.03). These findings warrant further evaluation in a clinical setting.

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Digital image analysis of bone allograft union in sheep

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Digital image analysis of bone allograft union in sheep

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