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Research Article

An Evidence-Based Systematic Review of Rosemary (Rosmarinus officinalis) by the Natural Standard Research Collaboration

Catherine Ulbricht Catherine Ulbricht is affiliated with the Massachusetts General Hospital, Boston, Massachusetts; Tracee Rae Abrams is affiliated with the University of Rhode Island, Kingston, Rhode Island; Ashley Brigham, James Ceurvels, Jessica Clubb, and Whitney Curtiss are affiliated with Northeastern University, Boston, Massachusetts; Catherine DeFranco Kirkwood, is affiliated with Anderson Cancer Center, Houston, Texas; Nicole Giese, is affiliated with Natural Standard Research Collaboration, Somerville, Massachusetts; Kevin Hoehn is affiliated with Faxton-St. Luke's Healthcare, Utica, New York; Ramon Iovin, Richard Isaac, Erica Rusie, Jill M. Grimes Serrano, Minney Varghese, Wendy Weissner, and Regina C. Windsor are affiliated with Natural Standard Research Collaboration, Somerville, Massachusetts.
, PharmD,
Tracee Rae Abrams Catherine Ulbricht is affiliated with the Massachusetts General Hospital, Boston, Massachusetts; Tracee Rae Abrams is affiliated with the University of Rhode Island, Kingston, Rhode Island; Ashley Brigham, James Ceurvels, Jessica Clubb, and Whitney Curtiss are affiliated with Northeastern University, Boston, Massachusetts; Catherine DeFranco Kirkwood, is affiliated with Anderson Cancer Center, Houston, Texas; Nicole Giese, is affiliated with Natural Standard Research Collaboration, Somerville, Massachusetts; Kevin Hoehn is affiliated with Faxton-St. Luke's Healthcare, Utica, New York; Ramon Iovin, Richard Isaac, Erica Rusie, Jill M. Grimes Serrano, Minney Varghese, Wendy Weissner, and Regina C. Windsor are affiliated with Natural Standard Research Collaboration, Somerville, Massachusetts.
, PharmD,
Ashley Brigham Catherine Ulbricht is affiliated with the Massachusetts General Hospital, Boston, Massachusetts; Tracee Rae Abrams is affiliated with the University of Rhode Island, Kingston, Rhode Island; Ashley Brigham, James Ceurvels, Jessica Clubb, and Whitney Curtiss are affiliated with Northeastern University, Boston, Massachusetts; Catherine DeFranco Kirkwood, is affiliated with Anderson Cancer Center, Houston, Texas; Nicole Giese, is affiliated with Natural Standard Research Collaboration, Somerville, Massachusetts; Kevin Hoehn is affiliated with Faxton-St. Luke's Healthcare, Utica, New York; Ramon Iovin, Richard Isaac, Erica Rusie, Jill M. Grimes Serrano, Minney Varghese, Wendy Weissner, and Regina C. Windsor are affiliated with Natural Standard Research Collaboration, Somerville, Massachusetts.
, PharmD,
James Ceurvels Catherine Ulbricht is affiliated with the Massachusetts General Hospital, Boston, Massachusetts; Tracee Rae Abrams is affiliated with the University of Rhode Island, Kingston, Rhode Island; Ashley Brigham, James Ceurvels, Jessica Clubb, and Whitney Curtiss are affiliated with Northeastern University, Boston, Massachusetts; Catherine DeFranco Kirkwood, is affiliated with Anderson Cancer Center, Houston, Texas; Nicole Giese, is affiliated with Natural Standard Research Collaboration, Somerville, Massachusetts; Kevin Hoehn is affiliated with Faxton-St. Luke's Healthcare, Utica, New York; Ramon Iovin, Richard Isaac, Erica Rusie, Jill M. Grimes Serrano, Minney Varghese, Wendy Weissner, and Regina C. Windsor are affiliated with Natural Standard Research Collaboration, Somerville, Massachusetts.
, PharmD,
Jessica Clubb Catherine Ulbricht is affiliated with the Massachusetts General Hospital, Boston, Massachusetts; Tracee Rae Abrams is affiliated with the University of Rhode Island, Kingston, Rhode Island; Ashley Brigham, James Ceurvels, Jessica Clubb, and Whitney Curtiss are affiliated with Northeastern University, Boston, Massachusetts; Catherine DeFranco Kirkwood, is affiliated with Anderson Cancer Center, Houston, Texas; Nicole Giese, is affiliated with Natural Standard Research Collaboration, Somerville, Massachusetts; Kevin Hoehn is affiliated with Faxton-St. Luke's Healthcare, Utica, New York; Ramon Iovin, Richard Isaac, Erica Rusie, Jill M. Grimes Serrano, Minney Varghese, Wendy Weissner, and Regina C. Windsor are affiliated with Natural Standard Research Collaboration, Somerville, Massachusetts.
, PharmD,
Whitney Curtiss Catherine Ulbricht is affiliated with the Massachusetts General Hospital, Boston, Massachusetts; Tracee Rae Abrams is affiliated with the University of Rhode Island, Kingston, Rhode Island; Ashley Brigham, James Ceurvels, Jessica Clubb, and Whitney Curtiss are affiliated with Northeastern University, Boston, Massachusetts; Catherine DeFranco Kirkwood, is affiliated with Anderson Cancer Center, Houston, Texas; Nicole Giese, is affiliated with Natural Standard Research Collaboration, Somerville, Massachusetts; Kevin Hoehn is affiliated with Faxton-St. Luke's Healthcare, Utica, New York; Ramon Iovin, Richard Isaac, Erica Rusie, Jill M. Grimes Serrano, Minney Varghese, Wendy Weissner, and Regina C. Windsor are affiliated with Natural Standard Research Collaboration, Somerville, Massachusetts.
, PharmD,
Catherine DeFranco Kirkwood Catherine Ulbricht is affiliated with the Massachusetts General Hospital, Boston, Massachusetts; Tracee Rae Abrams is affiliated with the University of Rhode Island, Kingston, Rhode Island; Ashley Brigham, James Ceurvels, Jessica Clubb, and Whitney Curtiss are affiliated with Northeastern University, Boston, Massachusetts; Catherine DeFranco Kirkwood, is affiliated with Anderson Cancer Center, Houston, Texas; Nicole Giese, is affiliated with Natural Standard Research Collaboration, Somerville, Massachusetts; Kevin Hoehn is affiliated with Faxton-St. Luke's Healthcare, Utica, New York; Ramon Iovin, Richard Isaac, Erica Rusie, Jill M. Grimes Serrano, Minney Varghese, Wendy Weissner, and Regina C. Windsor are affiliated with Natural Standard Research Collaboration, Somerville, Massachusetts.
, MPH, CCCJS-MAC,
Nicole Giese Catherine Ulbricht is affiliated with the Massachusetts General Hospital, Boston, Massachusetts; Tracee Rae Abrams is affiliated with the University of Rhode Island, Kingston, Rhode Island; Ashley Brigham, James Ceurvels, Jessica Clubb, and Whitney Curtiss are affiliated with Northeastern University, Boston, Massachusetts; Catherine DeFranco Kirkwood, is affiliated with Anderson Cancer Center, Houston, Texas; Nicole Giese, is affiliated with Natural Standard Research Collaboration, Somerville, Massachusetts; Kevin Hoehn is affiliated with Faxton-St. Luke's Healthcare, Utica, New York; Ramon Iovin, Richard Isaac, Erica Rusie, Jill M. Grimes Serrano, Minney Varghese, Wendy Weissner, and Regina C. Windsor are affiliated with Natural Standard Research Collaboration, Somerville, Massachusetts.
, MS,
Kevin Hoehn Catherine Ulbricht is affiliated with the Massachusetts General Hospital, Boston, Massachusetts; Tracee Rae Abrams is affiliated with the University of Rhode Island, Kingston, Rhode Island; Ashley Brigham, James Ceurvels, Jessica Clubb, and Whitney Curtiss are affiliated with Northeastern University, Boston, Massachusetts; Catherine DeFranco Kirkwood, is affiliated with Anderson Cancer Center, Houston, Texas; Nicole Giese, is affiliated with Natural Standard Research Collaboration, Somerville, Massachusetts; Kevin Hoehn is affiliated with Faxton-St. Luke's Healthcare, Utica, New York; Ramon Iovin, Richard Isaac, Erica Rusie, Jill M. Grimes Serrano, Minney Varghese, Wendy Weissner, and Regina C. Windsor are affiliated with Natural Standard Research Collaboration, Somerville, Massachusetts.
, PharmD, MBA, CGP,
Ramon Iovin Catherine Ulbricht is affiliated with the Massachusetts General Hospital, Boston, Massachusetts; Tracee Rae Abrams is affiliated with the University of Rhode Island, Kingston, Rhode Island; Ashley Brigham, James Ceurvels, Jessica Clubb, and Whitney Curtiss are affiliated with Northeastern University, Boston, Massachusetts; Catherine DeFranco Kirkwood, is affiliated with Anderson Cancer Center, Houston, Texas; Nicole Giese, is affiliated with Natural Standard Research Collaboration, Somerville, Massachusetts; Kevin Hoehn is affiliated with Faxton-St. Luke's Healthcare, Utica, New York; Ramon Iovin, Richard Isaac, Erica Rusie, Jill M. Grimes Serrano, Minney Varghese, Wendy Weissner, and Regina C. Windsor are affiliated with Natural Standard Research Collaboration, Somerville, Massachusetts.
, PhD,
Richard Isaac Catherine Ulbricht is affiliated with the Massachusetts General Hospital, Boston, Massachusetts; Tracee Rae Abrams is affiliated with the University of Rhode Island, Kingston, Rhode Island; Ashley Brigham, James Ceurvels, Jessica Clubb, and Whitney Curtiss are affiliated with Northeastern University, Boston, Massachusetts; Catherine DeFranco Kirkwood, is affiliated with Anderson Cancer Center, Houston, Texas; Nicole Giese, is affiliated with Natural Standard Research Collaboration, Somerville, Massachusetts; Kevin Hoehn is affiliated with Faxton-St. Luke's Healthcare, Utica, New York; Ramon Iovin, Richard Isaac, Erica Rusie, Jill M. Grimes Serrano, Minney Varghese, Wendy Weissner, and Regina C. Windsor are affiliated with Natural Standard Research Collaboration, Somerville, Massachusetts.
,
Erica Rusie Catherine Ulbricht is affiliated with the Massachusetts General Hospital, Boston, Massachusetts; Tracee Rae Abrams is affiliated with the University of Rhode Island, Kingston, Rhode Island; Ashley Brigham, James Ceurvels, Jessica Clubb, and Whitney Curtiss are affiliated with Northeastern University, Boston, Massachusetts; Catherine DeFranco Kirkwood, is affiliated with Anderson Cancer Center, Houston, Texas; Nicole Giese, is affiliated with Natural Standard Research Collaboration, Somerville, Massachusetts; Kevin Hoehn is affiliated with Faxton-St. Luke's Healthcare, Utica, New York; Ramon Iovin, Richard Isaac, Erica Rusie, Jill M. Grimes Serrano, Minney Varghese, Wendy Weissner, and Regina C. Windsor are affiliated with Natural Standard Research Collaboration, Somerville, Massachusetts.
, PharmD,
Jill M. Grimes Serrano Catherine Ulbricht is affiliated with the Massachusetts General Hospital, Boston, Massachusetts; Tracee Rae Abrams is affiliated with the University of Rhode Island, Kingston, Rhode Island; Ashley Brigham, James Ceurvels, Jessica Clubb, and Whitney Curtiss are affiliated with Northeastern University, Boston, Massachusetts; Catherine DeFranco Kirkwood, is affiliated with Anderson Cancer Center, Houston, Texas; Nicole Giese, is affiliated with Natural Standard Research Collaboration, Somerville, Massachusetts; Kevin Hoehn is affiliated with Faxton-St. Luke's Healthcare, Utica, New York; Ramon Iovin, Richard Isaac, Erica Rusie, Jill M. Grimes Serrano, Minney Varghese, Wendy Weissner, and Regina C. Windsor are affiliated with Natural Standard Research Collaboration, Somerville, Massachusetts.
, PhD,
Minney Varghese Catherine Ulbricht is affiliated with the Massachusetts General Hospital, Boston, Massachusetts; Tracee Rae Abrams is affiliated with the University of Rhode Island, Kingston, Rhode Island; Ashley Brigham, James Ceurvels, Jessica Clubb, and Whitney Curtiss are affiliated with Northeastern University, Boston, Massachusetts; Catherine DeFranco Kirkwood, is affiliated with Anderson Cancer Center, Houston, Texas; Nicole Giese, is affiliated with Natural Standard Research Collaboration, Somerville, Massachusetts; Kevin Hoehn is affiliated with Faxton-St. Luke's Healthcare, Utica, New York; Ramon Iovin, Richard Isaac, Erica Rusie, Jill M. Grimes Serrano, Minney Varghese, Wendy Weissner, and Regina C. Windsor are affiliated with Natural Standard Research Collaboration, Somerville, Massachusetts.
,
Wendy Weissner Catherine Ulbricht is affiliated with the Massachusetts General Hospital, Boston, Massachusetts; Tracee Rae Abrams is affiliated with the University of Rhode Island, Kingston, Rhode Island; Ashley Brigham, James Ceurvels, Jessica Clubb, and Whitney Curtiss are affiliated with Northeastern University, Boston, Massachusetts; Catherine DeFranco Kirkwood, is affiliated with Anderson Cancer Center, Houston, Texas; Nicole Giese, is affiliated with Natural Standard Research Collaboration, Somerville, Massachusetts; Kevin Hoehn is affiliated with Faxton-St. Luke's Healthcare, Utica, New York; Ramon Iovin, Richard Isaac, Erica Rusie, Jill M. Grimes Serrano, Minney Varghese, Wendy Weissner, and Regina C. Windsor are affiliated with Natural Standard Research Collaboration, Somerville, Massachusetts.
, BA &
Regina C. Windsor Catherine Ulbricht is affiliated with the Massachusetts General Hospital, Boston, Massachusetts; Tracee Rae Abrams is affiliated with the University of Rhode Island, Kingston, Rhode Island; Ashley Brigham, James Ceurvels, Jessica Clubb, and Whitney Curtiss are affiliated with Northeastern University, Boston, Massachusetts; Catherine DeFranco Kirkwood, is affiliated with Anderson Cancer Center, Houston, Texas; Nicole Giese, is affiliated with Natural Standard Research Collaboration, Somerville, Massachusetts; Kevin Hoehn is affiliated with Faxton-St. Luke's Healthcare, Utica, New York; Ramon Iovin, Richard Isaac, Erica Rusie, Jill M. Grimes Serrano, Minney Varghese, Wendy Weissner, and Regina C. Windsor are affiliated with Natural Standard Research Collaboration, Somerville, Massachusetts.
, MPH show all
Pages 351-413 | Published online: 22 Nov 2010
 
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ABSTRACT

An evidence-based systematic review of rosemary (Rosmarinus officinalis), including written and statistical analysis of scientific literature, expert opinion, folkloric precedent, history, pharmacology, kinetics/dynamics, interactions, adverse effects, toxicology, and dosing.

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Source: Elsevier BV
Ethnobotanical survey of the medicinal flora used by the Caribs of Guatemala.
Source: Elsevier BV
Production and Diversity of Volatile Terpenes from Plants on Calcareous and Siliceous Soils: Effect of Soil Nutrients
Source: HAL CCSD
Simple high-performance liquid chromatography method for α-tocopherol measurement in Rosmarinus officinalis leaves ☆: New data on α-tocopherol content
Source: Elsevier BV
Supplementing dietary rosemary (Rosmarinus officinalis L.) powder and vitamin E in broiler chickens: evaluation of humoral immune response, lymphoid organs, and blood proteins.
Source: Springer Science and Business Media LLC
Antimicrobial Screening of Some Turkish Medicinal Plants
Source: Informa UK Limited
Effects of olive, canola, and sunflower oils on the formation of volatiles from the Maillard reaction of lysine with xylose and glucose.
Source: American Chemical Society (ACS)
Recovery of phenolic antioxidants from wine industry by-products.
Source: Elsevier BV
II. Isolation of carnosic acid and formation of other phenolic diterpenes
Source: Springer Science and Business Media LLC
Anti-biofilm activity
Source: Wiley
Determination of antioxidant potential of volatile extracts isolated from various herbs and spices
Source: American Chemical Society (ACS)
Effects of industrially produced flavours with pro- and antioxidative properties on the formation of the heterocyclic amine PhIP in a model system.
Source: Elsevier BV
Characterization of Spanish unifloral honeys by solid phase microextraction and gas chromatography-mass spectrometry.
Source: Wiley
Rosemary Extract as a Potential Anti-Hyperglycemic Agent: Current Evidence and Future Perspectives.
Source: MDPI AG
Synergistic antileukemic activity of carnosic acid-rich rosemary extract and the 19-nor Gemini vitamin D analogue in a mouse model of systemic acute myeloid leukemia.
Source: S. Karger AG
Main agronomic-productive characteristics of two ecotypes of Rosmarinus officinalis L. and chemical composition of their essential oils.
Source: American Chemical Society (ACS)
Carnosol-induced apoptosis and downregulation of Bcl-2 in B-lineage leukemia cells.
Source: Elsevier BV
Supercritical Fluid Extracts of Rosemary Leaves Exhibit Potent Anti-Inflammation and Anti-Tumor Effects
Source: Informa UK Limited
Natural antioxidants as inhibitors of oxygen species induced mutagenicity.
Source: Elsevier BV
Inhibitory effect of commercial green tea and rosemary leaf powders on the growth of foodborne pathogens in laboratory media and oriental-style rice cakes.
Source: International Association for Food Protection
SHORT COMMUNICATION
Source: Wiley
Composition and insect attracting activity of the essential oil of Rosmarinus officinalis.
Source: Springer Science and Business Media LLC
Antimycotoxigenic characteristics of Rosmarinus officinalis and Trachyspermum copticum L. essential oils
Source: Elsevier BV
Effectiveness of immersion treatments with acids, trisodium phosphate, and herb decoctions in reducing populations of Yarrowia lipolytica and naturally occurring aerobic microorganisms on raw chicken.
Source: Elsevier BV
Experimental diuretic effects of Rosmarinus officinalis and Centaurium erythraea
Source: Elsevier BV
Subcellular compartmentation of the diterpene carnosic acid and its derivatives in the leaves of rosemary.
Source: American Society of Plant Biologists (ASPB)
Antimicrobial and chemopreventive properties of herbs and spices.
Source: Bentham Science Publishers Ltd.
Biosynthesis of pentahydroxystearic acid of cutin from linoleic acid in Rosmarinus officinalis
Source: Elsevier BV
Antibacterial activity of 11 essential oils against Bacillus cereus in tyndallized carrot broth
Source: Elsevier BV
Clinical safety and efficacy of NG440: a novel combination of rho iso-alpha acids from hops, rosemary, and oleanolic acid for inflammatory conditions.
Source: Canadian Science Publishing
Influence of antioxidants in virgin olive oil on the formation of heterocyclic amines in fried beefburgers
Source: Elsevier BV
OXIDATIVE STRESS MODULATION BY R. OFFICINALIS IN LIVER CIRRHOSIS
Source: Wiley
Direct determination of carnosic acid in a new active packaging based on natural extract of rosemary.
Source: Springer Science and Business Media LLC
Effect of antioxidants on the quality of irradiated sausages prepared with turkey thigh meat
Source: Elsevier BV
Inhibition of crown-gall tumorigenesis with plant extracts
Source: Informa UK Limited
Enantiomeric purity of (+/–)‐methyl jasmonate in fresh leaf samples and commercial fragrances
Source: Wiley-VCH
Effect of Commercial Rosemary Oleoresin Preparations on Ground Chicken Thigh Meat Quality Packaged in a High-Oxygen Atmosphere
Source: Elsevier BV
Protein glycation inhibitory and antioxidative activities of some plant extracts in vitro
Source: American Chemical Society (ACS)
Inhibitory effect of carnosic acid on HIV-1 protease in cell-free assays [corrected].
Source: American Chemical Society (ACS)
Essential oils from Mediterranean lamiaceae as weed germination inhibitors.
Source: American Chemical Society (ACS)
PREVENTION OF DENTAL BIOFILM
Source: Wiley
Oregano and rosemary extracts inhibit oxidation of long-chain n-3 fatty acids in menhaden oil.
Source: Wiley
EVALUATION OF ANTIOXIDANT ACTIVITY OF SOME NATURAL POLYPHENOLIC COMPOUNDS USING THE BRIGGS-RAUSCHER REACTION METHOD
Source: American Chemical Society (ACS)
In Vitro. Antimicrobial Activity of Some Libyan Medicinal Plant Extracts
Source: Informa UK Limited
Testing and Enhancing the in Vitro Bioaccessibility and Bioavailability of Rosmarinus officinalis Extracts with a High Level of Antioxidant Abietanes
Source: American Chemical Society (ACS)
Antibacterial Activities of Some Plant Extracts Used in Folk Medicine
Source: Informa UK Limited
Antioxidant activity of plant extracts containing phenolic compounds
Source: American Chemical Society (ACS)
Herbal Support for Methicillin-Resistant Staphylococcus aureus Infections
Source: Mary Ann Liebert Inc
Botanical Medicines for Headache
Source: Mary Ann Liebert Inc
Oxidation, reduction, and methylation of carnosic acid by Nocardia.
Source: American Chemical Society (ACS)
The detection of antibacterial actions of whole herb tinctures using luminescent Escherichia coli
Source: Wiley
Effects of plant extracts on microbial growth, color change, and lipid oxidation in cooked beef.
Source: Elsevier BV
Comparative evaluation of the antimicrobial activities of essential oils of Artemisia afra, Pteronia incana and Rosmarinus officinalis on selected bacteria and yeast strains.
Source: Wiley
Identification of phenolic compounds in rosemary honey using solid-phase extraction by capillary electrophoresis-electrospray ionization-mass spectrometry.
Source: Elsevier BV
Smelling lavender and rosemary increases free radical scavenging activity and decreases cortisol level in saliva
Source: Elsevier BV
Low-density lipoprotein, collagen, and thrombin models reveal that Rosemarinus officinalis L. exhibits potent antiglycative effects.
Source: American Chemical Society (ACS)
Effect of the addition of ground rosemary on the quality and shelf-life of turkey meatballs during refrigerated storage.
Source: Informa UK Limited
Chemical compositions and antioxidant properties of essential oils from nine species of Turkish plants obtained by supercritical carbon dioxide extraction and steam distillation
Source: Informa UK Limited
ANTIFUNGAL EFFECT OF VARIOUS OF ESSENTIAL OILS
Source: Wiley
Antimicrobial effect of spices and herbs on Shigella sonnei and Shigella flexneri.
Source: International Association for Food Protection
Carnosol inhibits the invasion of B16/F10 mouse melanoma cells by suppressing metalloproteinase-9 through down-regulating nuclear factor-kappaB and c-Jun
Source: Elsevier BV
Inhibition of 7,12-dimethylbenz[a]anthracene (DMBA)-induced mammary tumorigenesis and of in vivo formation of mammary DMBA-DNA adducts by rosemary extract.
Source: Elsevier BV
Antibacterial efficiency of Spanish Satureja montana essential oil against Listeria monocytogenes among natural flora in minced pork.
Source: International Association for Food Protection
In Vitro Antimicrobial Activity of Essential Oils from Aromatic Plants against Selected Foodborne Pathogens
Source: International Association for Food Protection
Development of In Vitro Models for Cellular and Molecular Studies in Toxicology and Chemoprevention
Source: Springer Berlin Heidelberg
Antioxidant activities of rosemary, sage, and sumac extracts and their combinations on stability of natural peanut oil.
Source: Mary Ann Liebert Inc
Multivariate Correlation between Color and Mineral Composition of Honeys and by Their Botanical Origin
Source: American Chemical Society (ACS)
Concomitant allergic contact dermatitis due to Rosmarinus officinalis (rosemary) and Thymus vulgaris (thyme).
Source: Wiley

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