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ARTICLE

An Evidence-Based Systematic Review of Bitter Orange (Citrus aurantium) by the Natural Standard Research Collaboration

Catherine UlbrichtMassachusetts General HospitalCorrespondence[email protected]

, PharmD,

Dawn CostaNatural Standard, 1 Davis Sq, Somerville, MA 02144

, BA,BS,

Nicole GieseNatural Standard, 1 Davis Sq, Somerville, MA 02144

, MS,

Richard IsaacNatural Standard, 1 Davis Sq, Somerville, MA 02144

Angela LiuNatural Standard, 1 Davis Sq, Somerville, MA 02144

Yanze LiuNatural Standard, 1 Davis Sq, Somerville, MA 02144

, PhD,

Olufemi OshoNatural Standard, 1 Davis Sq, Somerville, MA 02144

, PharmDc,

Linda PoonNatural Standard, 1 Davis Sq, Somerville, MA 02144

, PharmD,

Erica RusieNatural Standard, 1 Davis Sq, Somerville, MA 02144

, PharmD,

Tera StockNatural Standard, 1 Davis Sq, Somerville, MA 02144

, PharmD,

Wendy WeissnerNatural Standard, 1 Davis Sq, Somerville, MA 02144

, BA &

Regina C. WindsorNatural Standard, 1 Davis Sq, Somerville, MA 02144

, MPH show all

ABSTRACT

An evidence-based systematic review of bitter orange (Citrus aurantium) by the Natural Standard Research Collaboration consolidates the safety and efficacy data available in the scientific literature using a validated, reproducible grading rationale. This article includes written and statistical analysis of clinical trials, plus a compilation of expert opinion, folkloric precedent, history, pharmacology, kinetics/dynamics, interactions, adverse effects, toxicology, and dosing.

KEYWORDS. :

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An Evidence-Based Systematic Review of Bitter Orange (Citrus aurantium) by the Natural Standard Research Collaboration

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An Evidence-Based Systematic Review of Bitter Orange (Citrus aurantium) by the Natural Standard Research Collaboration

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