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Mitochondrial DNA Part A
DNA Mapping, Sequencing, and Analysis
Volume 27, 2016 - Issue 3
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Mitogenome Announcement

Whole mitochondrial genome sequencing and analysis for rat squamous cell carcinoma tissue cell

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Pages 2143-2144 | Received 17 Oct 2014, Accepted 27 Oct 2014, Published online: 26 Dec 2014
 

Abstract

Mitochondrial genome plays a central role in aging, cancer, apoptosis and metabolism. Squamous cell carcinoma is one of the major types of non–small cell lung cancer. We sequenced a complete mitochondrial genome sequence of a rat squamous cell carcinomas cell tissue for the first time. The total length of the mitochondrial genome was 16,319 bp, with 13 protein-coding genes, two ribosomal RNA genes and 22 transfer RNA genes. This genome describing information will supply the potential use of mtDNA mutations as markers in cancer.

Declaration of interest

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.

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