Complete mitochondrial genome sequence and mutations of the hepatocellular carcinoma model inbred Sprague–Dawley strain

Abstract

In the present work we undertook the complete mitochondrial genome sequencing of an important hepatocellular carcinoma model inbred Sprague–Dawley strain for the first time. The total length of the mitogenome was 16,308 bp. It harbored 13 protein-coding genes, two ribosomal RNA genes, 22 transfer RNA genes and one non-coding control region (D-loop region). The mutation events were also reported.

Keywords:

• Genome
• hepatocellular carcinoma
• mitochondrion

Declaration of interest

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the article. This study is supported by: the Natural Science Foundation of Fujian Province, No. 2012J01399.