Whole mitochondrial genome sequencing and analysis for chronic obstructive pulmonary disease rat strain

Zhi-ming JiangDepartment of Critical-care Medicine, Qianfoshan Hospital affiliated to Shandong University, Jinan, China and

Qing-sheng ZhaoDepartment of Thoracic Surgery, The People’s Hospital of Linyi, Linyi, China

Yong-qing XuDepartment of Critical-care Medicine, Qianfoshan Hospital affiliated to Shandong University, Jinan, China and

Tao LiDepartment of Critical-care Medicine, Qianfoshan Hospital affiliated to Shandong University, Jinan, China and

Jian JieDepartment of Critical-care Medicine, Qianfoshan Hospital affiliated to Shandong University, Jinan, China and

Zhong-hui ZhangDepartment of Critical-care Medicine, Qianfoshan Hospital affiliated to Shandong University, Jinan, China and Correspondence[email protected]

Abstract

Mitochondrial genome plays a central role in aging, cancer, apoptosis and metabolism. We sequenced a complete mitochondrial genome sequence of a rat chronic obstructive pulmonary disease rat strain for the first time. The total length of the mitochondrial genome was 16,310 bp and coding 13 protein-coding genes, two ribosomal RNA genes, 22 transfer RNA genes. This genome describing information will supply the potential use of mtDNA mutations as markers in cancer.

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Declaration of interest

The authors report no conflict of interest. The authors alone are responsible for the content and writing of the paper.

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Whole mitochondrial genome sequencing and analysis for chronic obstructive pulmonary disease rat strain

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Whole mitochondrial genome sequencing and analysis for chronic obstructive pulmonary disease rat strain

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