Nanomaterials and Optical Diagnosis of HIV

Abstract

The investigators had previously shown that the risk of AIDS/HIV-related illness and transmission reduced (by 96%) with early antiretroviral treatment. Nanomaterials could be applied in early diagnosis of HIV by improving the ability to detect serum biomarkers of the blood-borne infectious diseases, with low sample volume, rapidity, and more sensitivity than currently available FDA-approved methods such as ELISA, particle agglutination assay, and Western Blotting assay. We have demonstrated several experimental studies for optical HIV diagnosis based on nanomaterials in three categories (e.g., the fluorescence-, the SPR-, and the SERS- based biosensors), and have explained each assay.

Keywords::

• Diagnosis
• HIV
• Nanomaterials
• Nanotechnology

Acknowledgments

The authors are grateful for the financial support from the Department of Medical Nanotechnology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.

Declaration of interest

The authors report no declarations of interest. The authors alone are responsible for the content and writing of the paper.