ABSTRACT
The characteristics of the clinical course in long term CRPS are not known. We report 12 cases of complex regional pain syndrome of over ten year's duration with particular attention to complications of the condition. CRPS is associated with a movement disorder, spread of allodynia, migraine, depression and urological symptoms. All of our cases developed a movement disorder. In 58% the movement disorder was disabling, 83% developed total body allodynia, 67% became depressed, 58% had bladder dysfunction and migraine occurred in 50%. We conclude that long term CRPS can have severe neurological complications.