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Abstract
The occurrence of antibodies to Toxoplasma gondii was studied using the dye test (DT) and indirect haemagglutination test (IHA) with 1819 sera, mainly from patients with various diseases. Sera from 200 blood donors served as a control group. With both groups of sera, the qualitative agreement between the 2 tests was 75% and 79% respectively. If sera with low titres were excluded, the agreement was approximately 90%. IHA generally gave higher titres and a higher incidence of positive reactions than DT. Of the IHA-negative sera, only 6% were positive in the DT, while 33% of the DT-negative sera were positive in IHA. There was no accumulation of discordant sera according to diagnosis or sex, and no difference in incidence between patient and blood donor sera. The results indicate that IHA technique is applicable in a serological laboratory for determination of antibodies to toxoplasma. With the microtitre technique, large scale serological surveys could be done easily.