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Summary
The 7S and 19S distribution of blood group isoantibodies (isoagglutinins) has been measured in patients with systemic lupus erythematosus. The only possibly significant finding was a lower level of macroglobulin isoagglutinin to B cells in patients of blood type A. This is consistent with previous findings of lessened response to bacterial antigens by the macroglobulin antibody.