Two cases of reactive hemophagocytic syndrome: a patient with adult-onset Still's disease and a patient with herpes zoster and autoimmune abnormalities

Abstract

We report two cases of bone marrow hemophagocytosis. One patient had adult-onset Still's disease, and the other had herpes zoster associated with potential autoimmune abnormalities. Our findings suggested a pos-sible role of cytokines and/or antibodies in the induction of hemophagocytosis in patients with connective tissue diseases and/or immune abnormalities.

Key words::

• Adult-onset Still's disease (AOSD)
• Reactive hemophagocytic syndrome (HPS)
• Virus-associated hemophagocytic syndrome (VAHS)