Osteonecrosis and monoarticular rheumatoid arthritis treated with intra-articular adalimumab

Abstract

We report a 54-year-old patient with RA presented with osteonecrosis (ON) and monoarthritis of left knee remitting in the last 2 years. Monoarthritis was resistant to disease-modifying antirheumatic drugs (DMARDs) and intra-articular corticosteroids. Intra-articular administration of adalimumab provided a good clinical and radiographic response. Synovitis resolved and osteonecrosis disappeared almost totally.

Keywords::

• Monoarticular rheumatoid arthritis
• Osteonecrosis
• Adalimumab