A case of granuloma in the occipital lobe of a patient with Wegener’s granulomatosis

Abstract

We report a case of Wegener’s granulomatosis (WG) with central nervous system (CNS) involvement in a woman who complained of bilateral visual disturbance. The intracranial necrotizing granulomatous lesion was confirmed by MR imaging and brain biopsy. After high-dose oral corticosteroid treatment, not only clinical manifestations but also laboratory tests improved. Moreover, the CNS lesion completely regressed. This suggests that high-dose corticosteroid alone might be effective in treating WG with CNS involvement.

Keywords::

• Central nervous system involvement
• High-dose corticosteroid therapy
• Intracranial granuloma
• MR imaging
• Wegener’s granulomatosis