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Case Report

A case with life-threatening interstitial pneumonia associated with bucillamine treatment

, , , , &
Pages 522-525 | Received 10 Mar 2008, Accepted 17 Apr 2008, Published online: 02 Jan 2014
 

Abstract

We report a case of bucillamine-induced interstitial pneumonia accompanied by severe hypoxemia in an 83-year-old woman who had rheumatoid arthritis. Respiratory failure worsened even after withdrawal of bucillamine and administration of high-dose corticosteroids, and mechanical ventilation was required. A review of 15 cases with bucillamine-induced pulmonary injury suggests that advanced age may be associated with the development of severe interstitial pneumonia. Bucillamine can cause corticosteroid-resistant and life-threatening lung injury, especially in the elderly.

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