Epidural spinal tumor and periaortitis as rare complications of Wegener’s granulomatosis

Shimpei KasagiDepartment of Clinical Pathology and Immunology, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-Cho, Chuo-ku, Kobe, Hyogo 650-0017, JapanCorrespondence[email protected]

Jun SaegusaDepartment of Clinical Pathology and Immunology, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-Cho, Chuo-ku, Kobe, Hyogo 650-0017, Japan

Goh TsujiDepartment of Clinical Pathology and Immunology, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-Cho, Chuo-ku, Kobe, Hyogo 650-0017, Japan

Sho SendoDepartment of Clinical Pathology and Immunology, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-Cho, Chuo-ku, Kobe, Hyogo 650-0017, Japan

Natsuko MiuraDepartment of Clinical Pathology and Immunology, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-Cho, Chuo-ku, Kobe, Hyogo 650-0017, Japan

Hiroki HayashiDepartment of Clinical Pathology and Immunology, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-Cho, Chuo-ku, Kobe, Hyogo 650-0017, Japan

Takeshi SugimotoDepartment of Clinical Pathology and Immunology, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-Cho, Chuo-ku, Kobe, Hyogo 650-0017, Japan

Seiji KawanoDepartment of Clinical Pathology and Immunology, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-Cho, Chuo-ku, Kobe, Hyogo 650-0017, Japan

Kotaro NishidaDepartment of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan

Kenichiro KakutaniDepartment of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan

Akio MorinobuDepartment of Clinical Pathology and Immunology, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-Cho, Chuo-ku, Kobe, Hyogo 650-0017, Japan

Shunichi KumagaiDepartment of Clinical Pathology and Immunology, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-Cho, Chuo-ku, Kobe, Hyogo 650-0017, Japan

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Abstract

This case report describes findings in a 61-year-old woman who manifested scleritis, small pulmonary nodules, otitis media, periaortitis, and progressive epidural spinal tumor, associated with elevated serum myeloperoxidase anti-neutrophil cytoplasmic antibody (MPO-ANCA) levels. She was clinically diagnosed with Wegener’s granulomatosis, although vasculitis was not diagnosed due to the lack of typical histological findings. We discuss the differential diagnosis in this patient, and the association of MPO-ANCA with periaortitis or epidural spinal tumor.

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Epidural spinal tumor and periaortitis as rare complications of Wegener’s granulomatosis

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Epidural spinal tumor and periaortitis as rare complications of Wegener’s granulomatosis

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