Takayasu arteritis developing during treatment of ulcerative colitis with infliximab

Yoshiro HoraiUnit of Translational Medicine, Department of Immunology and Rheumatology, Nagasaki University, Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8501, JapanCorrespondence[email protected]

Oka SatoruUnit of Translational Medicine, Department of Immunology and Rheumatology, Nagasaki University, Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan

Samuel Lapalme-RemisDivision of Neurology, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada

Remi SumiyoshiUnit of Translational Medicine, Department of Immunology and Rheumatology, Nagasaki University, Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan

Yoshikazu NakashimaUnit of Translational Medicine, Department of Immunology and Rheumatology, Nagasaki University, Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan

Takahisa SuzukiUnit of Translational Medicine, Department of Immunology and Rheumatology, Nagasaki University, Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan

Akitomo OkadaUnit of Translational Medicine, Department of Immunology and Rheumatology, Nagasaki University, Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan

Shin-ya KawashiriUnit of Translational Medicine, Department of Immunology and Rheumatology, Nagasaki University, Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan

Kunihiro IchinoseUnit of Translational Medicine, Department of Immunology and Rheumatology, Nagasaki University, Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan

Mami TamaiUnit of Translational Medicine, Department of Immunology and Rheumatology, Nagasaki University, Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan

Satoshi YamasakiUnit of Translational Medicine, Department of Immunology and Rheumatology, Nagasaki University, Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan

Hideki NakamuraUnit of Translational Medicine, Department of Immunology and Rheumatology, Nagasaki University, Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan

Fuminao TakeshimaUnit of Translational Medicine, Department of Gastroenterology and Hepatology, Nagasaki University, Graduate School of Biomedical Sciences, Nagasaki, Japan

Tomoki OriguchiUnit of Translational Medicine, Department of Rehabilitation Sciences, Nagasaki University, Graduate School of Biomedical Sciences Biomedical Sciences, Nagasaki 852-8523, Japan

Atsushi KawakamiUnit of Translational Medicine, Department of Immunology and Rheumatology, Nagasaki University, Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan

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Abstract

A 22-year-old female with ulcerative colitis that was successfully treated with infliximab (IFX), and remained stable following tapered discontinuation of prednisolone, developed anterior neck pain and elevation of C-reactive protein following her fourth administration of IFX. She was diagnosed with Takayasu arteritis (TA) based on neck ultrasound and computed tomography angiography. This is the first report describing the development of TA during treatment of UC with IFX.

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Takayasu arteritis developing during treatment of ulcerative colitis with infliximab

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