Cyclosporin-A ameliorated interstitial pneumonitis in a patient with amyopathic dermatomyositis

M. AokiFirst Department of Internal Medicine, Nihon University School of Medicine, Oyaguchi-Kamimachi, Itabashi-ku, Tokyo 173-8610, Japan

Y. MatsukawaFirst Department of Internal Medicine, Nihon University School of Medicine, Oyaguchi-Kamimachi, Itabashi-ku, Tokyo 173-8610, Japan

M. KanekoFirst Department of Internal Medicine, Nihon University School of Medicine, Oyaguchi-Kamimachi, Itabashi-ku, Tokyo 173-8610, Japan

T. HattoriFirst Department of Internal Medicine, Nihon University School of Medicine, Oyaguchi-Kamimachi, Itabashi-ku, Tokyo 173-8610, Japan

T. ShimizuFirst Department of Internal Medicine, Nihon University School of Medicine, Oyaguchi-Kamimachi, Itabashi-ku, Tokyo 173-8610, Japan

S. NishinaritaFirst Department of Internal Medicine, Nihon University School of Medicine, Oyaguchi-Kamimachi, Itabashi-ku, Tokyo 173-8610, Japan

T. HorieFirst Department of Internal Medicine, Nihon University School of Medicine, Oyaguchi-Kamimachi, Itabashi-ku, Tokyo 173-8610, Japan

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Abstract

A 40-year-old woman with amyopathic dermatomyositis (ADM) developed acute pneumonitis. Despite pulse methylprednisolone therapy, the pneumonitis worsened. We therefore initiated cyclosporin-A (Cy-A) therapy with success, although Pneumocystis carinii (PC) pneumonia occurred. Coexistence of dermatomyositis (DM)-related pneumonitis and PC pneumonia was diagnosed by means of chest X-ray findings, KL-6, and polymerase chain reaction (PCR) for PC. We thus continued Cy-A therapy to ameliorate the pneumonitis. Cy-A appeared to be effective for corticosteroid-resistant pneumonitis in a patient with DM.

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Cyclosporin-A ameliorated interstitial pneumonitis in a patient with amyopathic dermatomyositis

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Cyclosporin-A ameliorated interstitial pneumonitis in a patient with amyopathic dermatomyositis

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