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Original Articles

Intravenous thrombolytic therapy for acute ischemic stroke

Weighing the risks and benefits of tissue plasminogen activator

, MD & , MD
Pages 221-231 | Published online: 30 Jun 2015
 

PREVIEW

Intravenous tissue plasminogen activator (tPA) is an important intervention in the treatment of acute ischemic stroke. However, if not administered according to strict guidelines, this therapy carries a substantial risk of intracerebral hemorrhage. The authors review trial data and patient selection criteria for tPA therapy and offer recommendations on effective stroke management in a clinical setting.

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