Inflammatory bowel disease

1. Origins, presentation, and course

Peter L. Moses Dr Moses and Dr Ferrentino are assistant professors and Dr Vecchio is associate professor and head, section of gastroenterology and hepatology; and Dr Moore is clinical instructor, department of medicine; University of Vermont College of Medicine, Burlington. Dr Bensen is assistant professor, Dartmouth Medical School, Hanover, New Hampshire, and a member of the department of gastroenterology, Veterans Administration Medical Center, White River Junction, Vermont.

, MD,

Brad R. Moore Dr Moses and Dr Ferrentino are assistant professors and Dr Vecchio is associate professor and head, section of gastroenterology and hepatology; and Dr Moore is clinical instructor, department of medicine; University of Vermont College of Medicine, Burlington. Dr Bensen is assistant professor, Dartmouth Medical School, Hanover, New Hampshire, and a member of the department of gastroenterology, Veterans Administration Medical Center, White River Junction, Vermont.

, MD,

Nicholas Ferrentino Dr Moses and Dr Ferrentino are assistant professors and Dr Vecchio is associate professor and head, section of gastroenterology and hepatology; and Dr Moore is clinical instructor, department of medicine; University of Vermont College of Medicine, Burlington. Dr Bensen is assistant professor, Dartmouth Medical School, Hanover, New Hampshire, and a member of the department of gastroenterology, Veterans Administration Medical Center, White River Junction, Vermont.

, MD,

Steven P. Bensen Dr Moses and Dr Ferrentino are assistant professors and Dr Vecchio is associate professor and head, section of gastroenterology and hepatology; and Dr Moore is clinical instructor, department of medicine; University of Vermont College of Medicine, Burlington. Dr Bensen is assistant professor, Dartmouth Medical School, Hanover, New Hampshire, and a member of the department of gastroenterology, Veterans Administration Medical Center, White River Junction, Vermont.

, MD &

James A. Vecchio Dr Moses and Dr Ferrentino are assistant professors and Dr Vecchio is associate professor and head, section of gastroenterology and hepatology; and Dr Moore is clinical instructor, department of medicine; University of Vermont College of Medicine, Burlington. Dr Bensen is assistant professor, Dartmouth Medical School, Hanover, New Hampshire, and a member of the department of gastroenterology, Veterans Administration Medical Center, White River Junction, Vermont.

, MD

PREVIEW

The exact cause of inflammatory bowel disease remains undiscovered, but its destructive nature is clearly recognized. In this article, the authors summarize what is known about the pathogenesis and epidemiology of ulcerative colitis and Crohn's disease and how to distinguish between the two, both clinically and pathologically. They also describe disorders that may mimic inflammatory bowel disease. In part 2 of this article, beginning on page 86, the authors discuss some of the therapeutic options that are commonly used as well as some that are investigational but show promise for patients with this chronic and relapsing disease.

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Inflammatory bowel disease

1. Origins, presentation, and course

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Inflammatory bowel disease

1. Origins, presentation, and course

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