PREVIEW
Various abnormalities of or trauma to the pituitary gland or hypothalamus can cause hypopituitarism. Resultant hormonal deficiencies may be partial and may take years to develop fully. Therefore, the clinical picture is often subtle and may include numerous manifestations, depending on the hormones involved and the patient's age at onset. In addition to discussing the causes of hypopituitarism, the authors of this article describe how to recognize and treat resulting hypothyroidism, adrenal insufficiency, hypogonadism, and growth-hormone deficiency.