PREVIEW
Although markers of liver disease are available, in many cases, their usefulness is limited by insufficient sensitivity or specificity. In addition, significant liver damage may already have occurred in patients who have normal findings on liver function tests. A basic understanding of abnormalities in liver enzymes is important to assist clinicians in developing a rational, cost-effective approach in patients with liver disease. In this article, Drs Gopal and Rosen discuss results of laboratory tests and how to use them in patient evaluation.