Genetic liver disease in adults

Early recognition of the three most common causes

Elizabeth D. Morrison Dr Morrison is senior fellow in gastroenterology/hepatology and Dr Kowdley is associate professor of medicine, University of Washington School of Medicine, and director, iron overload clinic, University of Washington Medical Center, Seattle.

, MD &

Kris V. Kowdley Dr Morrison is senior fellow in gastroenterology/hepatology and Dr Kowdley is associate professor of medicine, University of Washington School of Medicine, and director, iron overload clinic, University of Washington Medical Center, Seattle.Correspondence[email protected]

, MD

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The most common and clinically important genetic diseases leading to liver dysfunction in adults are Wilson's disease, hereditary hemochromatosis, and alpha [-antitrypsin deficiency. Although advances in molecular biology have led to the identification and characterization of the genetic defects in these disorders, gene testing has its strengths and limitations. Drs Morrison and Kowdley review these disorders and discuss how recent advances may affect patient care.

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Genetic liver disease in adults

Early recognition of the three most common causes

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Early recognition of the three most common causes

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