NSAID-related gastrointestinal injury

PREVIEW

In the United States, an estimated 15 million to 20 million people use nonsteroidal anti-inflammatory drugs (NSAIDs) on a long-term basis. With such statistics, it is not surprising that the most common side effect, gastrointestinal mucosal injury, remains a clinically important issue. Fortunately, this complication is largely preventable. In this review, Dr Fennerty focuses on the epidemiology, pathogenesis, risk factors, prevention, and treatment of NSAID-induced gastrointestinal injury and provides the reader with the data necessary to select care that prevents it.