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PREVIEW
In many patients with chronic hepatitis, no obvious cause can be found. Some of these patients have an overactive immune system reaction that is responsible for the chronic inflammation. Diagnosis can be difficult because autoantibodies and other typical features of autoimmunity are not present in all cases. In this article, Dr Luxon provides a roadmap through the maze of antibodies that are involved in autoimmune hepatitis and discusses current treatment options and evaluation of response to medical therapy.