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Postgraduate Medicine Volume 116, 2004 - Issue 5
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Original Articles

Treatment update on spondyloarthropathy

From NSAIDs and DMARDs to anti-TNF-α agents

Allen P. Anandarajah Dr Anandarajah is assistant professor of medicine, department of allergy, immunology and rheumatology, University of Rochester School of Medicine and Dentistry, Rochester, New York.
, MD &
Christopher T. Ritchlin Dr Ritchlin is associate professor of medicine, director of the Rheumatology Fellowship Training Program, and director of Clinical Immunology Research Center, department of allergy, immunology and rheumatology, University of Rochester School of Medicine and Dentistry.Correspondence[email protected]
, MD
Pages 31-40 | Published online: 30 Jun 2015
 
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Traditionally, nonsteroidal anti-inflammatory drugs (NSAIDs) and disease-modifying antirheumatic agents (DMARDs) have been used to control the symptoms of spondyloarthropathy. With the advent of anti-tumor necrosis factor a (anti-TNF-a) agents, however, it is now possible to slow disease progression, improve overall function, and provide symptomatic relief of arthritis, skin lesions, and bowel inflammation associated with these disorders. Here, Drs Anandarajah and Ritchlin explore the effectiveness of conventional therapies as well as biologic agents that are currently available or under development.

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