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Postgraduate Medicine Volume 122, 2010 - Issue 3
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Practice Pearl

Does the Choice of Statin Really Matter?

Carl J. Lavie The John Ochsner Heart and Vascular Institute, Department of Cardiovascular Diseases, Ochsner Health System, New Orleans, LACorrespondence[email protected]
, MD,
Richard V. Milani The John Ochsner Heart and Vascular Institute, Department of Cardiovascular Diseases, Ochsner Health System, New Orleans, LA
, MD &
James H. O'Keefe Mid America Heart Institute, Kansas City, MO
, MD
Pages 243-247 | Published online: 13 Mar 2015
 
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Practice Pearl

Switching from atorvastatin to generic simvastatin often results in worsening of LDL-C control in clinical practice, which can be prevented by using a 2-fold higher dose of simvastatin (this may not be advisable when using 40- or 80-mg atorvastatin doses).

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