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Abstract
The present investigation was carried out to assess the erythrocytic oxidative stress in post-parturient haemoglobinuria in buffaloes receiving sodium acid phosphate therapy daily till clinical recovery. Enhanced malondialdehyde levels indicating lipid peroxidation and very low reduced glutathione levels in erythrocytes of haemoglobinuric buffaloes suggested the involvement of oxidative stress in this disease. The decline of malondialdehyde levels to within normal limits and appreciable elevation of reduced glutathione levels following treatment with sodium acid phosphate revealed its antioxidant effects in haemoglobinuric buffaloes which seems to be the first report of its kind.