Strategic evaluation of interventions to prevent consequential late proctitis after prostate radiation therapy

Abstract

This review reconsiders evidence and strategies toward the prevention of consequential late rectal toxicity after radiation therapy, with a focus on prostate cancer. Novel clinical trial designs are encouraged, and these insights into the late effects of prostate radiation therapy have additional implications for late toxicity after cancer treatment for other tumors.

Keywords: :

• consequential late effects
• prostate radiation therapy
• symptom management
• proctitis
• late toxicity

10.4161/cbt.27822

Disclosure of Potential Conflicts of Interest

No potential conflicts of interest were disclosed.

Acknowledgments

T.N.S. is the recipient of a Clinical Investigator Team Leadership Award from the National Cancer Institute.