Cover Image: Cancer Biology & Therapy: Vol 4, No 4

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Abstract

Tumor suppressive effect of Adenovirus-p53 plus sodium butyrate therapy is demonstrated by TUNEL stain in treated KATO-III gastric cancer xenograft tumors in vivo. This study by Takimoto et al. from the laboratory of Dr. Yoshiro Niitsu, in this issue of Cancer Biology and Therapy, provides mechanistic insights into the beneficial effect of HDAC inhibition towards the anti-tumor effect of p53.

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