Abstract
It has become apparent that three dimensional culture systems more accurately mimic how cells act in vivo. In this issue of Cancer Biology & Therapy, Vertrees and colleagues describe a new three dimensional culture model for lung cancer. The scanning EM on this month’s cover shows a lung cell that was grown under normal culture conditions. To see the scanning EM of a lung cell grown in a three dimensional system and to learn how well these cells reflect what is happening in vivo, see the article by Vertrees et al.