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Abstract
Although mortality from cervical cancer declined for years after the widespread implementation of the Pap smear test, the incidence is again climbing-this time the more insidious adenocarcinoma. Cervical adenocarcinomas, in addition to having a worse prognosis than squamous cell carcinomas, are also more difficult to properly diagnose, making it imperative to identify good biomarkers for the disease. In the current issue of Cancer Biology & Therapy, Nakamura and colleagues describe villin 1 as a prognostic indicator for cervical adenocarcinoma. The cover image comes from their manuscript and shows a cervical squamous adenocarcinoma stained with an anti-villin 1 antibody (brown). To compare this section to other types of cervical or endometrial cancers and to learn more about villin 1 as a biomarker, see the article by Nakamura and colleagues.