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Abstract
Comment on: Cai L, et al. Mol Cell 2011; 42:426-37.
Figures and Tables
Figure 1 Metabolic regulation of gene expression as revealed through the yeast metabolic cycle (YMC). Intracellular acetyl-CoA levels increase during growth and induce the acetylation of histones to upregulate those genes specifically important for growth. Upon entry into stationary phase or quiescence, acetyl-CoA levels decrease, histones become deacetylated, and a group of genes associated with stress, starvation, and survival responses are upregulated. These genes are much less dependent on histone acetylation for their activation.
Comment on: Cai L, et al. Mol Cell 2011; 42:426 - 437