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Islets Volume 3, 2011 - Issue 6
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Research Paper

Islet vs. pancreas transplantation in Brazil: Defining criteria for pancreas allocation decision

Gustavo P.D. Sá São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Gastrosurgery Division; Department of Surgery; Federal University of São Paulo – Escola Paulista de Medicina; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil
,
Mari C. Sogayar São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil;; Chemistry Institute; Biochemistry Department; University of São Paulo; São Paulo, SP Brazil
,
Freddy G. Eliaschewitz São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil
,
Tércio Genzini São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil
,
Renato Letrinta São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil
,
Elton S. Onari Gastrosurgery Division; Department of Surgery; Federal University of São Paulo – Escola Paulista de Medicina; São Paulo, SP Brazil
,
Marluce Mantovani São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Chemistry Institute; Biochemistry Department; University of São Paulo; São Paulo, SP Brazil
,
Letícia Labriola São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Chemistry Institute; Biochemistry Department; University of São Paulo; São Paulo, SP Brazil
,
Delcio Matos Gastrosurgery Division; Department of Surgery; Federal University of São Paulo – Escola Paulista de Medicina; São Paulo, SP Brazil
,
Gaspar J. Lopes-Filho Gastrosurgery Division; Department of Surgery; Federal University of São Paulo – Escola Paulista de Medicina; São Paulo, SP Brazil
,
Adriano M. Gonzalez São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Gastrosurgery Division; Department of Surgery; Federal University of São Paulo – Escola Paulista de Medicina; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil
&
Thiago R. Mares-Guia São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; Cell and Molecular Therapy Center (NUCEL); University of São Paulo; São Paulo, SP Brazil;; Chemistry Institute; Biochemistry Department; University of São Paulo; São Paulo, SP Brazil
 show all
Pages 352-357 | Received 06 May 2011, Accepted 30 Aug 2011, Published online: 01 Nov 2011
 
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Abstract

Background: Many studies have evaluated whether there are characteristics related to pancreas donors and the islet isolation process that can influence in pancreatic islet yield. However, this analysis has not yet been performed in Brazil, one of the world leaders in whole pancreas organ transplantation (WOPT), where pancreas allocation for pancreatic islet transplantation (PIT) has no officially defined criteria. Definition of parameters that would predict the outcome of islet isolation from local pancreas donors would be useful for defining allocation priority in Brazil. Objective: To analyze the relationship between multiple donor-related and islet isolation variables with the total number of isolated pancreatic islet equivalents (IEQ) in a Brazilian sample of pancreas donors. Methods: Several variables were analyzed in 74 pancreata relative to the outcome of total IEQs obtained at the end of the process. Results: In univariate analysis, body mass index (BMI) (p = 0.003), the presence of fatty infiltrates in the pancreas as observed during harvesting (p = 0.042) and pancreas digestion time (p = 0.046) were identified as variables related to a greater IEQ yield. In a multivariate analysis a statistically significant contribution to the variability of islet yield was found only for the BMI (p = 0.017). A ROC curve defined a BMI = 30 as a cut-off point, with pancreata from donors with BMI > 30 yielding more islets than donors with BMI < 30 (p < 0.001). Conclusion: These data reinforces the importance of the donor BMI as a defining parameter for successful islet isolation and establishes this variable as a potential pancreas allocation criterion in Brazil, where there is an unequal competition for good quality organs between WOPT and PIT.

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