Repeated TALEs

Abstract

Three recent papers, published just weeks apart, describe the use of fluorescent TALEs to tag specific DNA sequences in live cells and, in one case, also in fixed cells, the latter with potential clinical applications.

Keywords: :

• DNA replication timing
• cell cycle
• centromeres
• single nucleotide polymorphisms
• telomeres
• transcription activator-like effectors

This article refers to:

10.4161/nucl.28143

Disclosure of Potential Conflicts of Interest

No potential conflict of interest was disclosed.

Acknowledgments

The cited work from the author’s laboratory was supported by grant MCB-1051398 from the U.S. National Science Foundation.