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Combining checkpoint inhibitors and BRAF-targeted agents against metastatic melanoma

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Article: e24320 | Received 07 Mar 2013, Accepted 15 Mar 2013, Published online: 01 May 2013
 

Abstract

The combination of BRAF-targeted agents with immune checkpoint inhibitors represents a recent advance in the treatment of melanoma, even though each of these therapeutic approaches alone has specific limitations. Increasing evidence suggests indeed the existence of a synergistic interaction between these therapeutic modalities.

Disclosure of Potential Conflicts of Interest

No potential conflicts of interest were disclosed.